Congratulations to Pfizer Andover, FOYA Winner for Facility Integration

In 2015, Pfizer launched “Project Indigo” to relocate clinical manufacturing capabilities from Chesterfield, Missouri, to the new 175,000 sq. ft., state-of-the-art Andover Clinical Manufacturing Facility (ACMF) on the existing Pfizer Andover campus. The move was made to expand clinical biological drug substance manufacturing capacity from 14 to 21 campaigns per year, while vertically integrating the Andover site through the co-location of early phase clinical manufacturing with large scale commercial manufacturing that was existing on the site.

With respect to scope, the ACMF is a five-story building, housing five independent manufacturing suites, dedicated to the development of new biotherapeutics and vaccines to support trials in disease areas including: oncology, rare diseases, infectious diseases, hemophilia, and rheumatoid arthritis. Capabilities include cell culture, microbial fermentation, associated downstream purification operations, and the required support areas for solution preparation.

Congratulations are also in order for the project’s supply partners and key participants, many of them local, who partnered with Pfizer to bring the ACMF project to fruition:

Engineer/Architect (A&E)

• CRB

Construction Manager

• Lendlease

Piping Subcontractors 

• Decco, Inc. (process)
• TG Gallagher Mechanical Contractors

HVAC Subcontractor

• McCusker Gill Inc.

Automation and Control Suppliers- 

• Schneider Electric (Building Automation)
• Hallam-ICS (Instruments & Controls)

Major Equipment Suppliers/Contractors

• WFI Generation Equipment – Aqua Chem Inc.
• Media and Buffer Prep Skids – Integrated Process Engineers and Constructors (IPEC)
• Bioreactor and CIP Skids – A&B Process Systems Corp.
• Disposable Bioreactors, Chromatography Columns and Skids – GE Healthcare

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