Novo Nordisk and Life Edit Therapeutics Establish Multi-Target Collaboration

Novo Nordisk and Life Edit Therapeutics, Inc., an ElevateBio company focused on next-generation gene editing technologies and therapeutics, today announced a research and development collaboration to discover and develop gene editing therapies against a select set of therapeutic targets.

With a focus on advancing base editing capabilities, Novo Nordisk will leverage Life Edit’s suite of gene editing technologies to precisely edit the genome with the aim of developing life-changing therapies for rare genetic disorders as well as more prevalent cardiometabolic diseases.

The collaboration between the two companies allows for development of up to seven programmes. Under the agreement, Life Edit will receive an upfront cash payment and is eligible to receive potential development, regulatory, and commercial milestones of 335 million US dollars for each of the first two development programmes under the collaboration and up to 250 million dollars for each of the following five development programmes under the collaboration. Novo Nordisk will be responsible for all research and development costs and Life Edit is also eligible to receive tiered royalties on future net sales of therapeutic products. In addition, Life Edit has an option to a global profit share on one programme.

Life Edit is part of ElevateBio’s integrated ecosystem of R&D platform technologies and end-to-end process development and cGMP manufacturing capabilities built to power the creation of life-transforming cell and gene therapies.

Read the full press release here .